Apheresis is an increasingly important procedure in the treatment of a vari
ety of conditions, sometimes performed via peripheral access because of con
cern over major complications associated with central venous catheter (CVC)
placement. This study sought to determine the safety and success for ultra
sound and fluoroscopically guided, non-tunneled dual lumen CVCs placed for
apheresis, Prospective data collection was made of 200 attempted CVC placem
ents in the radiology department utilizing real time sonographic guidance.
The complications relating to placement were noted in all and the number of
passes required for venepuncture and whether a single wall puncture was ac
hieved was recorded in 185 cases. Duration of catheterization and reason fo
r line removal were recorded in all, Our study group included 71 donors pro
viding peripheral blood stem cells for allogeneic transplant. CVCs were suc
cessfully placed in all patients, 191 lines in the internal jugular and sev
en in the femoral vein, 86.5% required only a single pass and 80.5% with on
ly anterior wall puncture. Inadvertent but clinically insignificant arteria
l puncture occurred in six (3%) cases. In no case did this prevent line pla
cement. There were no other procedure-related complications. 173 (87.4%) ca
theters were removed the same day. No catheters were removed prematurely. T
here was one case of prolonged venous bleeding. Our study demonstrates the
safety of central venous catheters for apheresis provided that duration of
catheterization is short and real-time sonographic guidance is used for the
puncture, and guide wire and catheter placement are confirmed fluoroscopic
ally.