Prolonged fatigue is a common symptom in the community and a common complai
nt in GPs' surgeries. The current consensus is that prolonged fatigue is mo
st appropriately managed within primary care but that quality of care is pa
tchy. Diagnosis is difficult and there is no conclusive evidence about effe
ctive treatment. This can lead to confusion and controversy among lay peopl
e and health professionals alike. Although the value of a positive doctor-p
atient relationship is emphasized, general practice consultations are frequ
ently experienced as difficult by both parties. Moreover, little is known a
bout how people access other sources of care and information about prolonge
d fatigue, such as alternative medicine, self-help groups, lay others, and
self care, in conjunction with or as an alternative to care from health pro
fessionals. This paper reviews the literature on the nature and extent of t
he problem prolonged fatigue represents for primary care, and on the use of
formal and informal care for prolonged fatigue.