A role for the small GTPase rho in epithelial cell invasion by Shigella

Authors
Adam, T
Citation
T. Adam, A role for the small GTPase rho in epithelial cell invasion by Shigella, B I PASTEUR, 96(2), 1998, pp. 93-102
Citations number
50
Categorie Soggetti
Immunology
Journal title
BULLETIN DE L INSTITUT PASTEUR
ISSN journal
00202452 → ACNP
Volume
96
Issue
2
Year of publication
1998
Pages
93 - 102
Database
ISI
SICI code
0020-2452(199804/06)96:2<93:ARFTSG>2.0.ZU;2-V
Abstract
The small GTPase rho has been shown to act as an important switch that link s signalling cascades initiated by cellular receptors to the cytoskeleton. While the important role of rho for major functions of probably all eukaryo tic cells has long been established, this review looks at this small GTPase as a regulator of cytoskeletal rearrangements during invasion of epithelia l cells by Shigella.