Severe cutaneous disease and injury often is best treated in the specialize
d treatment environment of a burn center Skilled burn treatment personnel c
ombine critical care expertise with extensive clinical experience in the ma
nagement of severe cutaneous injury and disease. In addition to thermal inj
ury, the burn center is the ideal environment for patients with progressive
toxic epidermal necrolysis, pemphigoid lesions, and invasive cutaneous inf
ection. Recent research indicates that the burn wound is a dynamic structur
e whose ultimate extent is modifiable by manipulations of the local anatomi
c and molecular environment. The many unanswered questions on the pathogene
sis and treatment of both the "medical" and "surgical" cutaneous processes
require close collaboration between the dermatologist and the burn team.