C. Nishijima et al., Urticarial vasculitis in systemic lupus erythematosus: fair response to prednisolone/dapsone and persistent hypocomplementemia, EUR J DERM, 9(1), 1999, pp. 54-56
Two cases of urticarial vasculitis (UV accompanying systemic lupus erythema
tosus (SLE) are reported. Both patients developed characteristic wheal and
purpuric lesions of UV followed by pigmentation, and histological examinati
on revealed leucocytoclastic vasculitis. Although oral prednisolone was ben
eficial for the systemic symptoms and various serological abnormalities, on
e patient needed dapsone and the other needed dapsone and cyclophosphamide
to control the UV. In both patients, hypocomplementemia with no evidence of
congenital complement deficiency or complement consumption persisted even
after all other laboratory data and symptoms improved.