Force-velocity relations of a two-state crossbridge model for molecular motors

Citation
A. Vilfan et al., Force-velocity relations of a two-state crossbridge model for molecular motors, EUROPH LETT, 45(3), 1999, pp. 283-289
Citations number
27
Categorie Soggetti
Physics
Journal title
EUROPHYSICS LETTERS
ISSN journal
02955075 → ACNP
Volume
45
Issue
3
Year of publication
1999
Pages
283 - 289
Database
ISI
SICI code
0295-5075(19990201)45:3<283:FROATC>2.0.ZU;2-R
Abstract
We discuss the force-velocity relations obtained in a two-state crossbridge model for molecular motors. They can be calculated analytically in two lim iting cases: for a large number and for one pair of motors. The effect of t he strain-dependent detachment rate on the motor characteristics is studied . It can lead to linear, myosin-like, kinesin-like and anomalous curves. In particular, we specify the conditions under which oscillatory behavior may be found.