Adenocarcinomas of the bifurcation of the hepatic ducts (Klatskin tumors) a
re a relatively rare cause of obstructive jaundice. Differential diagnosis
includes other neoplastic lesions, sclerosing cholangitis, Mirizzi's syndro
me and benign strictures. We present a 46 year-old white female with a 2 mo
nth history of epigastric pain and progressive jaundice. Endoscopic retrogr
ade cholangiopancreaticography (ERCP) revealed a filiform stenosis of the r
ight hepatic duct and an obstructed left hepatic duct, an image strongly su
ggestive of a Klatskin tumor. The correct diagnosis was achieved, however,
by percutaneous transhepatic cholangiography (PTC), which disclosed a galls
tone at the common hepatic duct bifurcation and multiple small concrements
in the left hepatic duct. After endoscopic removal of the gallstones in the
biliary tree and laparoscopic cholecystectomy, the patient was discharged
on the third post-operative day. Protuberant tumors and round biliary stone
s may be confused at ERCP.