A 73 year-old female patient suffered from anemia and a palpable abdominal
mass. Abdominal ultrasonography and magnetic resonance imaging revealed a l
esion with papillary excrescences at the pancreatic tail. Endoscopic retrog
rade cholangiopancreatography showed a normal pancreatic duct, but a small
submucosal tumor was found in the stomach incidentally. Laparotomy disclose
d an exophytic tumor arising from the submucosal layer of the stomach. Path
ology revealed a gastric leiomyosarcoma with remarkable liquefaction and cy
stic change. Gastric leiomyosarcoma can be so necrotic as to be mistaken fo
r a cystic tumor. It is critically important to differentiate the peripancr
eatic cystic lesion because the treatment strategy is totally different.