Analysis of 6 short tandem repeat loci in Navarre (Northern Spain)

Citation
M. Iriondo et al., Analysis of 6 short tandem repeat loci in Navarre (Northern Spain), HUMAN BIOL, 71(1), 1999, pp. 43-54
Citations number
55
Categorie Soggetti
Medical Research General Topics
Journal title
HUMAN BIOLOGY
ISSN journal
00187143 → ACNP
Volume
71
Issue
1
Year of publication
1999
Pages
43 - 54
Database
ISI
SICI code
0018-7143(199902)71:1<43:AO6STR>2.0.ZU;2-2
Abstract
A genetic study was performed on a sample of 146 autochthonous individuals from the province of Navarre (northern Spain) to test for 6 STR systems: CS F1PO, TPOX, TH01, F13A1, FES/FPS, and VWA31/A. The Navarre population has a series of allele frequencies that are at the extreme end of the European r ange of variation and that are in most cases similar to those found in the Basque population of the provinces of Alava, Biscay, and Guipuzcoa. This si milarity is corroborated by correspondence analysis, in which the populatio n of Navarre is at one end of the first axis with the Basque sample close t o it and the remaining European populations far removed, In tree-type repre sentations the Navarre population is grouped with the Basque series at 1 en d. Even so, the comparison of allele frequency distributions by the chi-squ are heterogeneity test indicates that these 2 groups are statistically diff erent. Our results together with the cultural relationship that exists betw een all the Basque-speaking provinces and the genetic heterogeneity describ ed in earlier studies between the Basque provinces of Alava, Biscay, and Gu ipuzcoa (Aguirre et al, 1989; Manzano, Orue et al. 1996; Manzano, Aguirre e t al, 1996) lead us to believe that the Navarre population lies within the heterogeneous Basque genetic map.