In a survey involving 281 patients awaiting assisted reproduction treatment
at five centres in three countries, and 289 population controls, we invest
igated whether the patients had experienced more negative emotional feeling
s and negative emotional impact during periods when they were attempting to
conceive as compared with the controls, and whether there was any differen
ce in their well-being at the time of consultation. The study was performed
in the context of currently divergent views as to the burden of fertility
problems, The survey was carried out using questionnaires of the self-admin
istration type. Women with fertility problems did in fact consistently repo
rt a higher prevalence of negative emotions than the controls with referenc
e to the periods during which they had been trying to conceive. Patients re
ported more changes in interpartner relationships (either negative or posit
ive). Sexuality was negatively affected among the patients, At the time of
consultation, the patients had less favourable scores than the controls on
scales for depressed mood, memory/concentration, anxiety and fears, as well
as for self-perceived attractiveness. One in four (24.9%) of the patients
had scores indicating depressive disorders as compared with only 6.8% of th
e controls. Current well-being was even more markedly affected in patients
with previous unsuccessful in-vitro fertilization (IVF) experience. The 'in
fertility' life event was perceived as severe by both patients and controls
. Both prior to consultation and during diagnosis and treatment, women with
fertility problems had a higher prevalence of reported negative psyche-emo
tional experiences than women without fertility problems.