Longitudinal involvement of the spinal cord in a patient with lupus related transverse myelitis

Transverse myelitis is a rare and serious complication of systemic lupus er ythematosus (SLE), Magnetic resonance imaging is the investigation of choic e fur diagnosis and followup, This typically shows T1 and T2 signal prolong ation, cord widening, and contrast enhancement over several spinal segments . We describe a 21-year-old woman with SLE who developed very extensive SLE related transverse myelitis with longitudinal involvement of the spinal co rd from C3 to T2 and from T7 to the conus medullaris, Clinically, this was manifest as leg weakness, bladder dysfunction, severe low back pain, and pa tchy lower limb sensory loss. She responded to treatment with pulse cycloph osphamide and high dose corticosteroids with complete recovery in 3 months. To our knowledge, this is the first case report of such an extensive "long itudinal" myelitis.