Nutritional effects of long-term gastrostomy feedings in children with cystic fibrosis

Citation
M. Rosenfeld et al., Nutritional effects of long-term gastrostomy feedings in children with cystic fibrosis, J AM DIET A, 99(2), 1999, pp. 191-194
Citations number
15
Categorie Soggetti
Food Science/Nutrition","Endocrynology, Metabolism & Nutrition
Journal title
JOURNAL OF THE AMERICAN DIETETIC ASSOCIATION
ISSN journal
00028223 → ACNP
Volume
99
Issue
2
Year of publication
1999
Pages
191 - 194
Database
ISI
SICI code
0002-8223(199902)99:2<191:NEOLGF>2.0.ZU;2-7
Abstract
Objective To analyze the long-term nutritional effects of supplemental gast rostomy feedings in undernourished patients with cystic fibrosis. Design Longitudinal, retrospective assessment of anthropometric measures be fore and for up to 4 years after gastrostomy. Subjects/setting All patients at a large cystic fibrosis care center who un derwent gastrostomy between 1980 and 1993 when they were at least 1 year ol d and were followed up for a minimum of 1 year after gastrostomy. Statistical analyses performed The Mann-Whitney U test was used to compare anthropometric values measured during 4 postgastrostomy time intervals with values measured during the year preceding gastrostomy. Results The 21 patients ranged in age from 1.1 to 20.8 years (median age = 7.4 years). They had mild to moderate malnutrition at the time of gastrosto my. Patients were followed up for a mean of 39 months after gastrostomy. Su pplemental feedings were associated with significant improvements in weight and height percentiles for age, and in weight as a percentage of ideal wei ght. Improvement in weight occurred earlier than improvement in height. Amo ng subjects followed up for at least 18 months after gastrostomy, median we ight percentile for age increased from 2% for the year before gastrostomy t o 12% for the period 6 to 18 months after gastrostomy (P < .001) and 19% fo r the period 30 to 48 months after gastrostomy (P = .002 compared with befo re gastrostomy). Other nutritional parameters followed similar, although le ss dramatic patterns. Gastrostomy feedings were well tolerated and associat ed with only minor complications. Conclusions Long-term gastrostomy feedings appear to be a safe and effectiv e means of improving nutrition in malnourished patients with cystic fibrosi s. Clinical dietitians should function as care managers for patients with c ystic fibrosis who are receiving supplemental gastrostomy feedings.