Small decreases in hydration status can result in a dramatic decrement in a
thletic performance and greatly increase the risk of thermal injury. Becaus
e of its osmotic properties, which enable greater fluid retention than the
ingestion of water alone, glycerol has been proposed as a hyperhydrating ag
ent. In fact, glycerol is now commercially available and marketed as a spor
t supplement to be ingested with water or sport drinks; thus, dietitians ne
ed to be cognizant of this new addition to the sports nutrition table. The
results of glycerol-induced hyperhydration research have been equivocal, mo
st likely because of methodologic differences between studies, such as vari
ations in the intensity of exercise, environmental conditions, and concentr
ation or dose of glycerol administered. Although the suggested dosage of gl
ycerol depends on body size and varies between manufacturers, 1 g/kg body w
eight with an additional 1.5 L fluid taken 60 to 120 minutes before competi
tion is standard. Some test subjects reported feeling bloated or nauseated
after ingesting glycerol. This review examines glycerol-induced hyperhydrat
ion research and the safety of ingesting glycerol, discusses commercial ava
ilability of glycerol, and makes recommendations for glycerol-induced hyper
hydration research.