Determination by 1D NOE studies of the stereochemistry of a tricyclic 2-hydroxytetrahydrofuran derivative obtained by hydroformylation of (1R)-(-)-myrtenol

Authors
Sirol, S Gorrichon, JP Kalck, P Nieto, PM Commenges, G
Citation
S. Sirol et al., Determination by 1D NOE studies of the stereochemistry of a tricyclic 2-hydroxytetrahydrofuran derivative obtained by hydroformylation of (1R)-(-)-myrtenol, MAGN RES CH, 37(2), 1999, pp. 127-132
Citations number
20
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
MAGNETIC RESONANCE IN CHEMISTRY
ISSN journal
07491581 → ACNP
Volume
37
Issue
2
Year of publication
1999
Pages
127 - 132
Database
ISI
SICI code
0749-1581(199902)37:2<127:DB1NSO>2.0.ZU;2-W
Abstract
The structure of a new, optically pure 2-hydroxytetrahydrofuran tricyclic c ompound resulting from the hydroformylation of (1R)-(-)-myrtenol was resolv ed by one- and two-dimensional H-1 and C-13 NMR. The configurations of the three new asymmetric centres are discussed on the basis of J(H,H) coupling constants, NOE measurements and molecular modelling. Copyright (C) 1999 Joh n Wiley & Sons, Ltd.