The cytoplasmic domain of FtsK protein is required for resolution of chromosome dimers

Authors
Steiner, W Liu, GW Donachie, WD Kuempel, P
Citation
W. Steiner et al., The cytoplasmic domain of FtsK protein is required for resolution of chromosome dimers, MOL MICROB, 31(2), 1999, pp. 579-583
Citations number
19
Categorie Soggetti
Microbiology
Journal title
MOLECULAR MICROBIOLOGY
ISSN journal
0950382X → ACNP
Volume
31
Issue
2
Year of publication
1999
Pages
579 - 583
Database
ISI
SICI code
0950-382X(199901)31:2<579:TCDOFP>2.0.ZU;2-U
Abstract
Chromosome dimers, formed by homologous recombination between sister chromo somes, normally require cell division to be resolved into monomers by site- specific recombination at the dif locus of Escherichia coli. We report here that it is not in fact cell division per se that is required for dimer res olution but the action of the cytoplasmic domain of FtsK, which is a bifunc tional protein required both for cell division and for chromosome partition .