Comparison of photorefractive keratectomy with excimer laser in situ keratomileusis in correcting low myopia (from -2.00 to -5.50 diopters) - A randomized study
Ma. El Danasoury et al., Comparison of photorefractive keratectomy with excimer laser in situ keratomileusis in correcting low myopia (from -2.00 to -5.50 diopters) - A randomized study, OPHTHALMOL, 106(2), 1999, pp. 411-420
Objective: To compare laser in situ keratomileusis (LASIK) with photorefrac
tive keratectomy (PRK) in the correction of myopia from -2.00 to -5.50 diop
ters.
Design: Prospective, randomized, paired clinical trial.
Participants: Fifty-two eyes of 26 myopic patients were enrolled in the stu
dy.
Intervention: Each patient received PRK on one eye (PRK eye) and LASIK on t
he other (LASIK eye); the procedure assigned to each eye, and the sequence
of surgeries for each patient was randomized.
Main Outcome Measures: Slit-lamp microscopy, manifest refraction, uncorrect
ed and spectacle-corrected visual acuity, and videokeratography were done b
efore operation, and 2 weeks, 6 weeks, 3 months, 6 months, and 12 months af
ter operation, Patient satisfaction and preference were assessed by a subje
ctive questionnaire.
Results: All LASIK eyes had fast, painless recovery. At 1 year, 24 patients
(92.3%) were examined, the mean spherical equivalent refraction was -0.08
+/- 0.38 diopter in the PRK eyes and -0.14 +/- 0.31 diopter in the LASIK ey
es, and the uncorrected visual acuity was 20/20 or better in 15 PRK eyes (6
2.5%) and 19 LASIK eyes (79.2%); no eye lost 2 or more Snellen lines of spe
ctacle-corrected visual acuity. Both procedures were stable throughout the
first year. One PRK eye developed dense subepithelial corneal haze. The str
ongest correlate to spectacle-corrected visual acuity after the two procedu
res was the coefficient of variation of corneal power over the pupil. Ninet
een patients (79.2%) preferred the LASIK procedure because of the fast, pai
nless recovery.
Conclusions: In the current study, PRK and LASIK were found to be similarly
effective, predictable, stable, and reasonably safe for the correction of
myopia between -2.00 and -5.50 diopters. Laser in situ keratomileusis has t
he advantage of fast, painless recovery. Patients prefer LASIK.