Shock impedance is an important determinant of defibrillation efficacy. Lea
d configuration, shock polarity, and delivered energy can affect shock impe
dance, but these variables have not been studied in active can lead systems
. The present study was a prospective evaluation of 25 patients undergoing
initial transvenous defibrillator implantation. In all patients, a dual coi
l lead and pectoral emulator were placed and three lead configurations were
tested in random order: Lead (distal to proximal coil), unipolar (distal c
oil to can), and triad (distal coil to can + proximal coil). Shock energies
of 0.1- to 15-J shock were evaluated. Impedance increased a mean of 21% as
delivered energy was decreased (P < 0.001), an effect independent of lead
configuration. At all delivered energies, impedances in the unipolar config
uration were about 40% higher than triad, while the lead configuration was
about 20% higher than triad tps ( 0.001). Polarity did not affect impedance
. These results indicate that transvenous lead configurations and delivered
energy, but not polarity, significantly influence shock impedance. The mag
nitude of the increase of impedance at low energies is independent of the s
hocking pathway. This effect has important implications for low energy shoc
ks used to terminate atrial fibrillation or ventricular tachycardia.