Fluconazole therapy in Candida albicans spondylodiscitis

A case of Candida albicans spondylodiscitis in a 20-year-old female liver t ransplant recipient is reported, The patient was successfully treated with sequential therapy with liposomal amphotericin B and fluconazole. A review of the literature showed 10 cases of Candida albicans spondylodiscitis succ essfully treated either with fluconazole alone or a sequential therapy with amphotericin B and fluconazole. If long-term amphotericin B therapy is not feasible, a prolonged course of fluconazole in a daily dose of 200-400 mg may be considered as an alternative.