A rare case of cotrimoxazole-induced eosinophilic aseptic meningitis in anHIV-infected patient

A case of cotrimoxazole-induced meningoencephalitis in an HIV-infected pati ent without signs of AIDS is reported. The patient developed an apparently generalized seizure, of cotrimoxazole, 1 month after first taking a dose of this drug and a febrile coma after a second dose 3 weeks later. Lumbar pun cture revealed eosinophilic aseptic meningitis. The patient quickly recover ed without sequelae and was given antiretroviral therapy plus pentamidine a erosolized and pyrimethamine as prophylaxis for opportunistic infections, N o other adverse effects were observed. The report describes the diagnosis o f this case supported by a commentary, including a literature review.