Sustained complete remission after chemobiohormonal therapy for metastaticmelanoma

Authors
Stein, ME Bernstein, Z Drumea, K Zalik, M Shklar, Z Steiner, M Haim, N
Citation
Me. Stein et al., Sustained complete remission after chemobiohormonal therapy for metastaticmelanoma, AM J CL ONC, 22(1), 1999, pp. 62-64
Citations number
5
Categorie Soggetti
Oncology
Journal title
AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
ISSN journal
02773732 → ACNP
Volume
22
Issue
1
Year of publication
1999
Pages
62 - 64
Database
ISI
SICI code
0277-3732(199902)22:1<62:SCRACT>2.0.ZU;2-W
Abstract
The combination of carmustine, cisplatin, dacarbazine interferon, and low-d ose tamoxifen is widely used in treating metastatic melanoma and was origin ally reported to acheive a 20% complete response rate. Among 29 patients wh o completed the authors' phase TI study with the regimen, five (17%) achiev ed complete remission, and the median duration of response was 8 months (ra nge, 2-14 months). The aim of the study was to evaluate briefly the value a nd toxicity of this regimen in treating metastatic malignant melanoma.