Early-onset scleral necrosis after iodine I 125 plaque radiotherapy for ciliochoroidal melanoma

Authors
Correa, ZM Augsburger, JJ Freire, J Eagle, RC
Citation
Zm. Correa et al., Early-onset scleral necrosis after iodine I 125 plaque radiotherapy for ciliochoroidal melanoma, ARCH OPHTH, 117(2), 1999, pp. 259-261
Citations number
4
Categorie Soggetti
Optalmology,"da verificare
Journal title
ARCHIVES OF OPHTHALMOLOGY
ISSN journal
00039950 → ACNP
Volume
117
Issue
2
Year of publication
1999
Pages
259 - 261
Database
ISI
SICI code
0003-9950(199902)117:2<259:ESNAII>2.0.ZU;2-7
Abstract
A 62-year-old man with a large ciliochoroidal melanoma developed early-onse t scleral necrosis with tumor extrusion within 1 month of epibulbar iodine I 125 plaque radiotherapy. The eye was enucleated. Pathologic study reveale d nonmicrobial scleral necrosis with extrusion of histologically intact and necrotic uveal melanoma cells. The patient has been followed up for 15 mon ths without clinical recurrence. We discuss possible mechanisms to explain the early development of scleral necrosis after plaque therapy in this pati ent.