Differential diagnosis of monoclonal gammopathies

Authors
Alexanian, R Weber, D Liu, F
Citation
R. Alexanian et al., Differential diagnosis of monoclonal gammopathies, ARCH PATH L, 123(2), 1999, pp. 108-113
Citations number
16
Categorie Soggetti
Research/Laboratory Medicine & Medical Tecnology","Medical Research Diagnosis & Treatment
Journal title
ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE
ISSN journal
00039985 → ACNP
Volume
123
Issue
2
Year of publication
1999
Pages
108 - 113
Database
ISI
SICI code
0003-9985(199902)123:2<108:DDOMG>2.0.ZU;2-7
Abstract
Several disorders are associated with a monoclonal immunoglobulin detected by serum or urine electrophoresis, the most common being a monoclonal gammo pathy of undetermined significance, multiple myeloma, Waldenstrom's macrogl obulinemia, and amyloidosis. The clinical features of these conditions, as well as other similar entities, are described in this review. The objective is to demonstrate the importance of electrophoretic studies in the differe ntial diagnosis of plasma cell dyscrasias and in guiding the decision for r ational therapies.