Association between serotonin transporter gene polymorphism and anxiety-related traits

Background: Polymorphism in the serotonin transporter promoter gene has bee n recently reported to be associated with the personality trait known as an xiety-related traits. We have attempted to replicate these findings in 101 healthy Japanese subjects. Methods: The personality traits of the subjects were assessed with the trid imensional personality questionnaire. Results: An association,was observed in rite present study between individu als grouped according to the transporter gene and harm avoidance scores. Conclusions: These data supported that there was an association between the serotonin transporter gene and anxiety. Biol Psychiatry 1999:45:368-370 (C ) 1999 Society of Biological Psychiatry.