Many organic compounds interact with the ethylene receptor and diffuse free
after different periods of time. Some are agonists and mimic ethylene, and
some are antagonists, which prevent ethylene action by blocking the recept
or. Some of the antagonists have proven useful in scientific studies, and s
ome promise to be commercially important in protecting against ethylene. Th
e times that different compounds remain bound may be important clues to how
ethylene transmits its signal to the signal transduction pathway. Ethylene
diffuses from the site with a t(1/2) of 2-10 minutes and is an active comp
ound. For 2,5-Norbornadiene (2,5-NBD) and some other strained olefins that
block ethylene action, the half diffusion time is 3-6 h. For other more str
ained compounds (cyclopropenes) the half diffusion time is estimated to be
7-12 days; they block ethylene action during this time. The time of diffusi
on from the receptor appears to be the major difference between compounds t
hat block the receptor and those that are active. It is suggested that this
time constant may be the controlling factor in ethylene action.