CYCLOCONDENSATION OF N-(2-BROMOETHYL)PHTHALIMIDE WITH THE DIANION OF ISOBUTYRIC ACID TO A FUNCTIONALIZED 2,3-DIHYDROOXAZOLO[2,3]ISOINDOL-5(9BH)-ONE DERIVATIVE
N. Dekimpe et al., CYCLOCONDENSATION OF N-(2-BROMOETHYL)PHTHALIMIDE WITH THE DIANION OF ISOBUTYRIC ACID TO A FUNCTIONALIZED 2,3-DIHYDROOXAZOLO[2,3]ISOINDOL-5(9BH)-ONE DERIVATIVE, Journal of chemical research. Synopses, (6), 1995, pp. 252-253
Contrary to a previous report describing that the condensation or N-(2
-bromoethyl)phthalimide with the dianion of isobutyric acid affords -1
-yl)carbonyl]phenyl}-2,2-dimethyl-3-oxopropanoic acid, we report that
this reaction in fact leads to drooxazolo[2,3-a]isoindol-9b-yl)-2-meth
ylpropanoic acid.