Population based analysis of pesticide kinetics

Citation
N. Von Gotz et al., Population based analysis of pesticide kinetics, CHEMOSPHERE, 38(7), 1999, pp. 1615-1630
Citations number
10
Categorie Soggetti
Environment/Ecology
Journal title
CHEMOSPHERE
ISSN journal
00456535 → ACNP
Volume
38
Issue
7
Year of publication
1999
Pages
1615 - 1630
Database
ISI
SICI code
0045-6535(199903)38:7<1615:PBAOPK>2.0.ZU;2-#
Abstract
Kinetic evaluations play an essential role in the registration procedure of drugs and pesticides for quantifying the exposition of organisms to the ap plied chemicals. Population based analysis methods provide a means for redu cing experimental effort for parameter estimation and are meanwhile well es tablished in pharmaceutical research. In spite of many similarities between pesticide and drug development, this promising procedure up to now has not been transferred to environmental sciences. In this paper, we show that po pulation based analysis works equally well in environmental sciences as in pharmacokinetics. As an example, the evaluation of pesticide degradation in several soils is presented.