Thrombolysis may favorably affect the clinical outcome of mobile right atri
al thrombus following pulmonary embolism (PE). We report the case of three
patients with mobile right atrial thrombus following PE, in whom fibrinolys
is was performed. Atrial mass disappeared on the control echocardiogram, bu
t control ventilation perfusion scan showed new perfusion defects in all pa
tients. Thrombolysis seems successful for the treatment of patients with mo
bile right atrial thrombus following PE; however, recurrent PE may be induc
ed by fibrinolysis. This may affect the benefit of such therapy and should
be taken into account when using this therapeutic treatment.