Lower extremity counterpart of the Poland syndrome

Below-the-knee right leg hypoplasia and ipsilateral toe brachysyndactyly we re observed in a 4-year-old female with an otherwise normal phenotype. Elec tromyographic and nerve conduction studies were normal. The Doppler evaluat ion was consistent with a 50% reduction in the blood supply from the femora l artery, suggesting vascular disruption as the pathogenic mechanism. Our observations support the hypothesis that a lower extremity counterpart of the Poland syndrome does exist and that the extent of limb involvement i s dependent on the level of vascular disruption.