Comparative characteristics of the Israeli Newcastle disease virus field strains by means of a wide panel of monoclonal antibodies against hemagglutinin-neuraminidase glycoprotein

Authors
Panshin, A Shihmanter, E Weisman, Y Orvell, C Lipkind, M
Citation
A. Panshin et al., Comparative characteristics of the Israeli Newcastle disease virus field strains by means of a wide panel of monoclonal antibodies against hemagglutinin-neuraminidase glycoprotein, COMPAR IMM, 22(2), 1999, pp. 103-124
Citations number
50
Categorie Soggetti
Veterinary Medicine/Animal Health
Journal title
COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES
ISSN journal
01479571 → ACNP
Volume
22
Issue
2
Year of publication
1999
Pages
103 - 124
Database
ISI
SICI code
0147-9571(199904)22:2<103:CCOTIN>2.0.ZU;2-H
Abstract
Fourteen mouse monoclonal antibodies (MAB) were tested for their ability to react with 15 reference and 52 local Newcastle disease virus (NDV) strains isolated in Israel during the last decade from feral birds. All the field isolates had no antigenic difference when examined by classic serological t ests. However, MAB-mediated analysis revealed wide antigenic heterogeneity amongst the studied viruses. By the pattern of the MAB reactivity, all the isolates could be distributed into 13 groups. (C) 1999 Elsevier Science Ltd . All rights reserved.