A software implementation for detailed volume conductor modelling in electrophysiology using finite difference method

Citation
P. Kauppinen et al., A software implementation for detailed volume conductor modelling in electrophysiology using finite difference method, COMPUT M PR, 58(2), 1999, pp. 191-203
Citations number
22
Categorie Soggetti
Multidisciplinary
Journal title
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE
ISSN journal
01692607 → ACNP
Volume
58
Issue
2
Year of publication
1999
Pages
191 - 203
Database
ISI
SICI code
0169-2607(199902)58:2<191:ASIFDV>2.0.ZU;2-U
Abstract
There is an evolving need for new information available by employing patien t tailored anatomically accurate computer models of the electrical properti es of the human body. Because construction of a computer model can be diffi cult and laborious to perform sufficiently well, devised models have varied greatly in the level of anatomical accuracy incorporated in them. This has restricted the validity of conducted simulations. In the present study, a versatile software package was developed to transform anatomic voxel data i nto accurate finite difference method volume conductor models conveniently and in a short time. The package includes components for model construction , simulation, visualisation and detailed analysis of simulation output base d on volume conductor theory. Due to the methods developed, models can comp rise more anatomical details than the prior computer models. Several models have been constructed, for example, a highly detailed 3-D anatomically acc urate computer model of the human thorax as a volume conductor utilising th e US National Library of Medicine's (NLM) Visible Human Man (VHM) digital a natomy data. Based on the validation runs the developed software package is readily applicable in analysis of a wide range of bioelectric field proble ms. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.