Extremozymes

Citation
Dw. Hough et Mj. Danson, Extremozymes, CURR OP C B, 3(1), 1999, pp. 39-46
Citations number
64
Categorie Soggetti
Biochemistry & Biophysics
Journal title
CURRENT OPINION IN CHEMICAL BIOLOGY
ISSN journal
13675931 → ACNP
Volume
3
Issue
1
Year of publication
1999
Pages
39 - 46
Database
ISI
SICI code
1367-5931(199902)3:1<39:E>2.0.ZU;2-I
Abstract
Extremozymes offer new opportunities for biocatalysis and biotransformation s as a result of their extreme stability. From recent work, major approache s to extending the range of applications of extremozymes have emerged. Both the discovery of new extremophilic species and the determination of genome sequences provide a route to new enzymes, with the possibility that these will lead to novel applications. Of equal importance, protein engineering a nd directed evolution provide approaches to improve enzyme stability and mo dify specificity in ways that may not exist in the natural world.