Adsorption of calcitonin to glass

Surface adsorption of calcitonin on soda lime silica glass was investigated An attempt was also made to examine the effect of additives on the inhibit ion of calcitonin adsorption. Results showed that the adsorption isotherms were of the Langmuir and Freundlich type, depending on pH. Less adsorption was found for calcitonin at pH, 4.3. The addition of nonionic surfactants s uch as Pluronic F68 and Tween 80 to the calcitonin solutions demonstrated i nhibition of adsorption and reduction of adsorption rate. The addition of c hlorobutanol also showed the effect of minimizing adsorption.