A clinical study was made of the use of romifidine in the preanesthetic med
ication of the ketamine-halothane anesthesia in horses. Romifidine, an alph
a-2-adrenoceptor agonist, was administered intravenously at 80 mu g/kg to 7
2 horses. Anesthesia was induced parenterally (ketamine, 2.2 mg/kg) and mai
ntained with halothane. Heart rate respiratory rate and rectal temperature
were recorded both at rest and curing anesthesia. The following clinical pa
rameters were noted: quality of sedation, type of induction, quality of tra
nsition to inhalational anesthesia, quality of anesthesia, recumbency time
and recovery time. The use of romifidine with ketamine and halothane result
ed in gentle induction, maintenance and recovery from anesthesia.