Capillary electrophoresis of subcellular-sized particles

Utilization of capillary electrophoresis (CE) for characterization and anal ytical separation of submicron- and micron-sized organic and inorganic part icles as well as biological vesicles is reviewed. CE has been applied to ch arged polystyrene size standards, inorganic and organic colloidal particles , lipoprotein particles, liposomes, microsomes and viruses. These particle separations generally occur in a size-dependent manner and provide values o f electrophoretic mobility which are in good agreement with those obtained by other electrophoretic techniques. (C) 1999 Elsevier Science B.V. All rig hts reserved.