Axinellamines A-D, novel imidazo-azolo-imidazole alkaloids from the Australian marine sponge Axinella sp.

Authors
Urban, S Leone, PD Carroll, AR Fechner, GA Smith, J Hooper, JNA Quinn, RJ
Citation
S. Urban et al., Axinellamines A-D, novel imidazo-azolo-imidazole alkaloids from the Australian marine sponge Axinella sp., J ORG CHEM, 64(3), 1999, pp. 731-735
Citations number
8
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
JOURNAL OF ORGANIC CHEMISTRY
ISSN journal
00223263 → ACNP
Volume
64
Issue
3
Year of publication
1999
Pages
731 - 735
Database
ISI
SICI code
0022-3263(19990205)64:3<731:AANIAF>2.0.ZU;2-M
Abstract
Four imidazo-azolo-imidazole alkaloids, axinellamines A-D, have been isolat ed from an Australian marine sponge, Axinella sp. (order: Halichondrida: fa mily: Axinellidae). These compounds contain a unique perhydrocyclopenta-imi dazo-azolo-imidazole carbon skeleton. Three of these compounds had bacteric idal activity against Helicobacter pylori at 1000 mu M.