The neonatal presentation of Prader-Willi syndrome revisited

We describe 6 newborns evaluated for hypotonia, later diagnosed with Prader -Willi syndrome despite the absence of the classical neonatal features of t his syndrome. Specific genetic testing for Prader-Will; syndrome should be considered for all neonates with undiagnosed central hypotonia even in the absence of the other major features of this syndrome.