Adrenal cancer with hypertension but low plasma renin and aldosterone

Patients with malignant lesions of the adrenal gland may present with a syn drome of excess mineralocorticoids. Both primary hyperaldosteronism and exc ess mineralocorticoids other than aldosterone resulting from adrenal carcin oma hale rarely been reported. In most patients with adrenal tumors secreti ng mineralocorticoids other than aldosterone, distant metastasis had alread y occurred at the time of diagnosis and the prognosis was poor. MTC present a rare case of adrenal cancer with hypertension in a patient with low plas ma renin activity and a low plasma aldosterone concentration. The patient's blood pressure returned to normal after removal of the tumor. The patient is still alive and without recurrence 6 years after surgery. This case illu strates the value of thorough evaluation of hypertension and prompt surgica l treatment for patients with adrenal cancer.