Srs. Gottesman et al., Peripheral T cell lymphoma in a patient with common variable immunodeficiency disease: Case report and literature review, LEUK LYMPH, 32(5-6), 1999, pp. 589-595
This report documents the occurrence of a peripheral T cell lymphoma arisin
g in the bone marrow and liver of a patient with common variable immunodefi
ciency disease. The T cell origin of this lymphoma was demonstrated by immu
nohistochemical phenotyping and gene rearrangement studies and was not asso
ciated with EBV infection of the lymphoma cells. The frequency and characte
ristics of lymphomas complicating CVID are reviewed.