SURGICAL-TREATMENT OF INVASIVE PENILE CANCER - THE HEIDELBERG EXPERIENCE FROM 1968 TO 1994

Objectives: This study was performed to establish oncological guidelin es for the surgical treatment of invasive penile cancer. Materials and Methods: The medical records of 51 patients with invasive penile canc er seen between 1968 and 1994 were reviewed in respect to treatment an d long-term outcome. Results: For stage T1 tumors treated with organ-p reserving procedures the local recurrence rats was 56%, whereas no pat ient experienced a local recurrence after partial amputation. For stag e T2 tumors, local recurrence rate was 100% (organ preservation) versu s 20% (amputative procedures). There was no significant difference rel ated to regional recurrence between surveillance, inguinal radiation a nd lymphadenectomy for stage NO tumors. For N+ stages, survival was re lated to the extent of inguinal metastasis after dissection (5-year su rvival rate for N1: 71 vs. 33% for N2/3). Conclusions: Organ-preservin g procedures include a high risk of local and regional recurrence. Adj uvant regional lymphadenectomy seems beneficial only in patients with solitary metastasis.