Preparations containing Xylazine and Tiletamin-Zolazepam active ingredients
mere used in a pilot study involving 15 Holstein-Friesian crossbred calves
of both sexes to evaluate them for the purpose of anaesthesia in computer-
assisted tomography (CT). The animals were assigned to three groups of equa
l sizes. In Groups 1 and 2 Xylazine (Rometar) was administered intravenousl
y vs, intramuscularly, respectively, while in Group 3 a mixture of Tiletami
n-Zolazepam (I:I) (Zoletil), was administered intramuscularly. Times to lie
down, of subsequent immobility, to regain consciousness and to full recove
ry were recorded. The physiological status of calves was monitored while th
ey were anaesthetised. In accordance with relevant literature data, intrave
nous administration of Xylazine resulted in lying down and narcosis more ra
pidly than was the case with intramuscular application. Since only 15 minut
es are required for (CT) examination when anaesthesia can be reversed with
an antidote (e.g Yohimbin), thus a continuous working routine can be achiev
ed. Similarly to other species, there were substantial within-group deviati
ons observed in the recorded parameters of the calves revealing different l
evels of individual sensitivity to identical doses of the anaesthetic. The
preliminary results obtained in this study indicate that the Tiletamin-Zola
zepam anaesthetic combination is suitable for effective application in calv
es for CT examination without any substantial side-effects.