Plasma exchange versus intravenous immunoglobulin treatment in myasthenic crisis

Authors
Qureshi, AI Choudhry, MA Akbar, MS Mohammad, Y Chua, HC Yahia, AM Ulatowski, JA Krendel, DA Leshner, RT
Citation
Ai. Qureshi et al., Plasma exchange versus intravenous immunoglobulin treatment in myasthenic crisis, NEUROLOGY, 52(3), 1999, pp. 629-632
Citations number
9
Categorie Soggetti
Neurology,"Neurosciences & Behavoir
Journal title
NEUROLOGY
ISSN journal
00283878 → ACNP
Volume
52
Issue
3
Year of publication
1999
Pages
629 - 632
Database
ISI
SICI code
0028-3878(199902)52:3<629:PEVIIT>2.0.ZU;2-W
Abstract
We performed a retrospective multicenter chart review to compare the effica cy and tolerance of plasma exchange (PE) and intravenous immunoglobulin (IV Ig) in treatment of 54 episodes of myasthenic crisis. After adjustment for other variables, PE (compared with Mg) was associated with a superior venti latory status at 2 weeks (partial F = 6.2, p = 0.02) and 1 month functional outcome (partial F = 4.5, p = 0.04). However, the complication rate was hi gher with PE compared with IVIg (13 versus 5 episodes, p = 0.07).