1. Bright light exposure has been demonstrated as an effective treatment fo
r circadian rhythm sleep disorders. Recent studies suggest that more modera
te intensities of light might affect endogenous rhythms. A light mask treat
ment, using light applied through eyelids during sleep, was tested for Dela
yed Sleep Phase Syndrome.
2. The active light group (n=5) received <(500 lux)under bar> light for 3 h
ours prior to awakening for 12 days. The placebo light group (n=5) received
<(0.1 lux)under bar> light with the same timing. Circadian rhythm phase wa
s assessed from core body temperature and urinary 6-sulfatoxymelatonin meas
urements. The SIGH-SAD-SR mood scale was administered to assess mood.
3. There were slight trends toward a phase advance of the body temperature
rhythm and a phase delay of the melatonin rhythm, and both groups reported
anti-depressant benefits. However, no statistically significant effects of
500 lux light mask treatment were demonstrated compared with the placebo-li
ght treatment.
4. More extensive studies will be required to clarify the factors of dose-r
esponse and phase-response.