This report reviews developments in the early diagnosis and staging of pros
tate cancer and updated on the incidence of postate cancer to discuss the p
ros and cons of population based screening. Refinements and reliability of
various diagnosic procedures are described such as PSA testing, transrectal
ultrasound, ratio beteen PSA-level and ultrasound measured prostate volume
, rate of change of PSA-level, combination factor equations computed by neu
ral network programs to predict likelihood of prostate cancer, artificial n
eural network analysis of subvisual transrectal ultrasound information, mea
surements of different PSA-forms of PSA (in particular percent free PSA), a
nd glandular kallikrein 2.