Advanced prostate cancer

Both the definition and therapy of advanced prostate cancer is challenging. The advanced prostate cancer session at "The 8th International Prostate Ca ncer Update" had discussions which tried to answer the questions of managem ent of these patients who either present with advanced disease or fail any form of therapy for clinically confined prostate cancer. This article provi des an overview of therapeutic options: monotherapy and minimal androgen bl ockade options versus maximal androgen blockade, adjuvant therapy, intermit tent therapy and timing of therapy as well as chemotherapy when all these m easures fail. The impact of these therapies on progression as well as quali ty of life is reviewed.