Unbalanced translocation with partial 6p trisomy and partial 11q monosomy:a case report

Chromosomal rearrangements involving either the short rm of chromosome 6 or the long arm of chromosome II ave been reported in the literature. The phe notyc effects of such aberrations include growth failure, developmental del ay and a costellation of dysmorphisms and functional defects of various org ans. To the best of our knowledge, unbalanced translocation involving both chromosome 6 and 11 have never been observed, so far. Here we report on the clinical findings observed in a patients with a unbal anced translocation causing 6p trisomy and 11q monosomy.