ALPHA-ARYLATION OF KETONES BY ARYLLEAD TRIACETATES - EFFECT OF METHYLAND PHENYL SUBSTITUTION AT THE ALPHA-POSITION

Authors
MORGAN J PINHEY JT ROWE BA
Citation
J. Morgan et al., ALPHA-ARYLATION OF KETONES BY ARYLLEAD TRIACETATES - EFFECT OF METHYLAND PHENYL SUBSTITUTION AT THE ALPHA-POSITION, Journal of the Chemical Society. Perkin transactions. I, (7), 1997, pp. 1005-1008
Citations number
31
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of the Chemical Society. Perkin transactions. I → ACNP
ISSN journal
0300922X
Issue
7
Year of publication
1997
Pages
1005 - 1008
Database
ISI
SICI code
0300-922X(1997):7<1005:AOKBAT>2.0.ZU;2-7
Abstract
An examination of the alpha-arylation of a number of ketones and their enolate salts by p-methoxyphenyllead triacetate provides further evid ence for a very marked selectivity in the arylation reaction. It is fo und that the reaction proceeds well at tertiary alpha-carbons and at s econdary centres activated by the presence of a phenyl group, but fail s where the secondary centre is unactivated and at primary alpha-carbo ns.