The objective of this review is to evaluate the measurement tools currently
used in the study of eccentric contraction-induced muscle injury, with emp
hasis on their usefulness for quantifying the magnitude and duration of the
injury and as indicators of muscle functional deficits. In studies in huma
ns, it was concluded that measurements of maximal voluntary contraction tor
que and range of motion provide the best methods for quantifying muscle inj
ury. Similarly, in animal studies, the in vitro measurement of electrically
elicited force under isometric conditions was considered to be the best of
the measurement tools currently in use.
For future studies, more effort should be put into measuring other contract
ile parameters (e.g. force/torque-velocity and force/torque-length relation
ships, maximal shortening velocity and fatigue susceptibility) that may ref
lect injury-induced functional impairments. The use of histology, ratings o
f soreness and the measurement of blood or bath levels of myofibre proteins
should be discouraged for purposes of quantifying muscle injury and/or fun
ctional impairment.