Debromination of 8-bromo-2 '-deoxyguanosine by methylene blue and visible light

Authors
Venkatarangan, L Yang, DH Epling, GA Basu, AK
Citation
L. Venkatarangan et al., Debromination of 8-bromo-2 '-deoxyguanosine by methylene blue and visible light, TETRAHEDR L, 40(8), 1999, pp. 1441-1444
Citations number
14
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
8
Year of publication
1999
Pages
1441 - 1444
Database
ISI
SICI code
0040-4039(19990219)40:8<1441:DO8'BM>2.0.ZU;2-X
Abstract
Debromination of 8-bromo-2'-deoxyguanosine was accomplished in high yield u nder neutral conditions in aqueous methanol by irradiating with visible lig ht in the presence of methylene blue as a sensitizer and triethylamine as a n electron donor. The method can be extended for the debromination of other bromoaromatic compounds. (C) 1999 Elsevier Science Ltd. Ail rights reserve d.