Debromination of 8-bromo-2'-deoxyguanosine was accomplished in high yield u
nder neutral conditions in aqueous methanol by irradiating with visible lig
ht in the presence of methylene blue as a sensitizer and triethylamine as a
n electron donor. The method can be extended for the debromination of other
bromoaromatic compounds. (C) 1999 Elsevier Science Ltd. Ail rights reserve
d.