Direct evidence for the importance of hydrophobic mismatch for cell membrane recognition

Authors
Ghebremariam, B Sidorov, V Matile, S
Citation
B. Ghebremariam et al., Direct evidence for the importance of hydrophobic mismatch for cell membrane recognition, TETRAHEDR L, 40(8), 1999, pp. 1445-1448
Citations number
18
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
8
Year of publication
1999
Pages
1445 - 1448
Database
ISI
SICI code
0040-4039(19990219)40:8<1445:DEFTIO>2.0.ZU;2-Q
Abstract
In this Letter, we describe the synthesis of amphiphilic oligo(p-phenylene) s from 31 to 44 Angstrom length and delineate the interaction of these rigi d-rod molecules with lipid bilayers using fluorescence quenching methods. T he results demonstrate high importance of hydrophobic mismatch for selectiv e cell membrane recognition by rigid-rod molecules. (C) 1999 Elsevier Scien ce Ltd. All rights reserved.