Mt. Barros et al., The alkylation of a novel acetal derived from (2R,3R)-(+)-tartaric acid: An unexpected rearrangement, TETRAHEDR L, 40(8), 1999, pp. 1583-1586
The novel chiral bis-acetal dioxane 2a derived from (2R,3R)-(+)-tartaric ac
id was shown to undergo an unexpected rearrangement upon treatment with lit
hium amide base to give the chiral dioxolane 3a in optically active form. A
lkylation and aldol studies were performed on the diisopropyl ester of this
dioxolane 3b. (C) 1999 Elsevier Science Ltd. All rights reserved.